Investorideas.com
Search  Follow Investorideas on Twitter  Investorideas is on Facebook  Investorideas is on Google Plus  Investorideas is on Youtube  Investorideas is on Pinterest  Investorideas is on tumblr  Investorideas is on LinkedIn  Investorideas RSS 


Investorideas podcasts on iTunes, Google Play Music and iHeart.com    Bitcoin and Blockchain Stocks


Immunotherapy Firm's Technology Demonstrates 'Potential Use in Treating Cancers and Bacterial Infections'

Source: Streetwise Reports

 

September 28, 2017 (Investorideas.com Newswire) H.C. Wainwright & Co. reported the results of animal studies conducted using therapeutics created by this cancer and chronic infectious disease vaccine developer.


Analyst Ram Selvaraju, with H.C. Wainwright & Co., noted in a Sept. 22 research report that Inovio Pharmaceuticals Inc. (INO:NASDAQ) announced publication in medical journals of two of its preclinical studies involving its plasmid DNA-encoded monoclonal antibody (dMAb) products. He reported that Inovio's dMAb technology demonstrated "potential use in treating cancers and bacterial infections in addition to viral infections."

The trial of Inovio's dMAb therapeutic against prostate-specific membrane antigen, the results of which were published in Cancer Immunology, Immunotherapy, showed "the construct produced monoclonal antibodies that controlled growth of human prostate cancer cells in transgenic mice and prolonged survival," Selvaraju reported.

The analyst reiterated that Inovio's anti-cancer dMAb products work by "binding the antigens on the cancer cells and killing them by an antibody-dependent cytotoxicity mechanism in conjunction with natural killer cells."

The second trial, published in Nature Communications, was of the biotech's dMAb immunotherapy that encodes two pseudomonas antigens. It revealed that "the construct had indistinguishable potency compared to bioprocessed immunoglobulin G and protected against lethal pneumonia in mice," wrote Selvaraju. "Prior publications demonstrated utility of dMAb constructs in treating viral infections, such as the publication on influenza infections that appeared in July 2017."

Inovio's therapeutics that target antibiotic-resistant bacteria "are designed to generate bispecific monoclonal antibodies, which could simultaneously bind two different antigens," he reminded readers.

In response to the findings outlined in the articles, Selvaraju concluded, "These two new publications further validate the dMAb technology platform and expand its potential use in treating a variety of cancers and bacterial infections." Additionally, he wrote, "These novel mechanisms could provide multiple shots on goal and warrant potential future use of dMAb products in combination with other therapeutics."

An advantage to Inovio's technology, Selvaraju indicated, is it "enables patients' own cells to become the factory that manufactures the therapeutic monoclonal antibody products, and overcomes the limitations of conventional monoclonal antibodies that are manufactured outside the body in bioreactors in terms of cost effectiveness and product stability."

Further, the development time frame for Inovio's dMAb products "might be shortened as the platform allows the company to bypass difficulties faced by traditional protein-based mAb technology," explained Selvaraju.

The first dMAb therapeutic Inovio will advance to human trials is for Ebola viral infections, the analyst reported. That's scheduled to occur in 2018.

H.C. Wainwright has a rating of Buy and a price target of $13 per share on Inovio, which is currently trading at around $6.29 per share.

Read what other experts are saying about:

Disclosure:

1) Doresa Banning compiled this article for Streetwise Reports LLC and provides services to Streetwise reports as an independent contractor. She or members of her household own securities of the following companies mentioned in the article: None. She or members of her household are paid by the following companies mentioned in this article: None.

2) The following company mentioned in this article is a sponsor of Streetwise Reports: Inovio Pharmaceuticals Inc. Streetwise Reports does not accept stock in exchange for its services. Click here for important disclosures about sponsor fees. The information provided above is for informational purposes only and is not a recommendation to buy or sell any security.

3) Comments and opinions expressed are those of the specific experts and not of Streetwise Reports or its officers.

4) The article does not constitute investment advice. Each reader is encouraged to consult with his or her individual financial professional and any action a reader takes as a result of information presented here is his or her own responsibility. By opening this page, each reader accepts and agrees to Streetwise Reports' terms of use and full legal disclaimer. This article is not a solicitation for investment. Streetwise Reports does not render general or specific investment advice and the information on Streetwise Reports should not be considered a recommendation to buy or sell any security. Streetwise Reports does not endorse or recommend the business, products, services or securities of any company mentioned on Streetwise Reports.

5) From time to time, Streetwise Reports LLC and its directors, officers, employees or members of their families, as well as persons interviewed for articles and interviews on the site, may have a long or short position in securities mentioned. Directors, officers, employees or members of their immediate families are prohibited from making purchases and/or sales of those securities in the open market or otherwise from the time of the interview or the decision to write an article, until one week after the publication of the interview or article.


BiotechIndustryStocks.com - A Leading Global Investor Website for Biotech Industry Stocks

BiotechIndustryStocks.com - investing ideas in biotechnology stocks, medical technology and life sciences

Like Biotech Stocks? View our Biotech Stocks Directory

Get News Alerts on Biotech Stocks


More Info:

Investorideas.com Newswire

This news is published on the Investorideas.com Newswire - a global digital news source for investors and business leaders

Disclaimer/Disclosure: Investorideas.com is a digital publisher of third party sourced news, articles and equity research as well as creates original content, including video, interviews and articles. Original content created by investorideas is protected by copyright laws other than syndication rights. Our site does not make recommendations for purchases or sale of stocks, services or products. Nothing on our sites should be construed as an offer or solicitation to buy or sell products or securities. All investment involves risk and possible loss of investment. This site is currently compensated for news publication and distribution, social media and marketing, content creation and more. Contact each company directly regarding content and press release questions. Disclosure is posted for each compensated news release, content published /created if required but otherwise the news was not compensated for and was published for the sole interest of our readers and followers. More disclaimer info: http://www.investorideas.com/About/Disclaimer.asp

Additional info regarding BC Residents and global Investors: Effective September 15 2008 - all BC investors should review all OTC and Pink sheet listed companies for adherence in new disclosure filings and filing appropriate documents with Sedar. Read for more info: http://www.bcsc.bc.ca/release.aspx?id=6894. Global investors must adhere to regulations of each country.


Questrade Democratic Pricing - 1 cent per share, $4.95 min / $9.95 max



Join Investor Ideas Members to access the Renewable Energy stocks directory, water stocks, biotech stocks, defense stocks directories and the Insiders Corner